CDC recommends that people 65 years and older and those who are moderately or severely immunocompromised receive a second dose of the 2024-25 COVID-19 vaccine six months after their first dose.
The recommendation acknowledges the increased risk of severe disease from COVID-19 in older adults and those who are immunocompromised, along with the currently available data on vaccine effectiveness and year-round circulation of COVID-19.
Data continues to confirm the importance of vaccination to protect those most at risk for severe outcomes of COVID-19.
Receiving recommended 2024-2025 COVID-19 vaccines can restore and enhance protection against the virus variants currently responsible for most infections and hospitalizations in the United States.
COVID-19 vaccination also reduces the chance of suffering the effects of Long COVID.